强效镇痛药调控麻醉诱导中循环功能的比较

The Effects of Potent Narcotics on Hemodynamics during Induction of Anesthesia

本文比较苏芬太尼和二氢埃托啡在全麻快诱导中对循环功能的影响。结果：（１）静脉应用二氢埃托啡和苏芬太尼，在控制气管插管的心血管副反应时效价比约为２：１；（２）苏芬太尼１．２ｕｇ／ｋｇ或二氢埃托啡０．６ｕｇ／ｋｇ均可抑制气管插管时血压和心率的大幅度增加，而０．６ｕｇ／ｋｇ的苏芬太尼则效果不佳；（３）在同时保持气管插管前后的心脏射血功能上，二氢埃托啡不如苏芬太尼。

uring induction with sufentanil and dihydroetorphine the hemodynamic changes were studied in 18 patients.Results:(1)The suppression effect of dihydroetorphine on cardiovascular response to laryngoscopy and intubationwas nearly twice as potent as that of sufentanil;(2)Both of 1.2ug/kg sufentanil and 0.6ug/kg dihydroetorphineprevented effectively the increase of heart rate and blood pressure during endotracheal intubation,but 0.6ug/kgsufentanil did not (3)Sufenfanil seemed to be better for the maintenance of left ventricular function.