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软脂酸和花生四烯酸对人肝细胞瘤细胞株细胞葡萄糖摄取的影响 被引量：4

Effects of palmitic acid and arachidonic acid on the glucose uptake of HepG2 cells
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摘要 脂肪酸对人肝细胞瘤细胞株(HepG2)细胞葡萄糖摄取研究显示,高浓度的软脂酸可通过抑制HepG2细胞胰岛素受体和葡萄糖转运子2的表达抑制胰岛素刺激的葡萄糖摄取;花生四烯酸可通过类似机制刺激葡萄糖摄取,部分阻断软脂酸的作用。 The study of effects of fatty acids on HepG2 cells showed that palmitic acid at high concentration decreased glucose uptake of HepG2 cells possibly through inhibiting the expression of Ins receptor and GluT2 proteins. Arachidonic acid stimulated glucose uptake through the similar mechanism with preventing the inhibitory effects of palmitic acid.
作者 王平 母义明 汪保安 潘长玉
机构地区 解放军总医院内分泌科
出处 《中华糖尿病杂志（1006-6187）》 CSCD 北大核心 2005年第2期140-141,共2页
关键词 软脂酸 花生四烯酸 肝细胞瘤 细胞株 细胞葡萄糖 糖摄取 HepG2 胰岛素 Palmitic acid Arachidonic acid Glucose uptake
分类号 R735.7 [医药卫生—肿瘤]
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参考文献7

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二级参考文献2

共引文献8

同被引文献46

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引证文献4

二级引证文献5

中华糖尿病杂志（1006-6187）
2005年 第2期

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