老年抑郁症治疗方案分析

Analysis of treatment for depression in elderly

目的:分析老年抑郁症治疗方案的特点和疗效,促进合理治疗。方法:采用自编表格收集51例住院病人的治疗情况并进行分析。结果:老年抑郁症病人首选SSRIs等新型抗抑郁药治疗,67%的病人采用改良电休克治疗(MECT),MECT合并药物治疗起效快、MECT组(n=34)比对照组(n=17)病人临床痊愈率高,分别为47%和12%(P<0.05);92%的病人合并使用苯二氮艹卓类药物。结论:住院老年抑郁症病人适用MECT合并新型抗抑郁药治疗,疗效明显优于单用药物治疗,心理治疗有待加强。

AIM： To analyze the characteristics and efficacy of treatment for the senile depression for promoting the proper management. METHODS： Fifty-one eider inpatients with depression were recruited.A special designed schedule was adopted to analyse the data of the result. RESULTS： SSRIs are recommended as the first choice antidepressants for the elder depressions. Modify electroconvulsive therapy （MECT）was applied to 67 % of the inpatients, and MECT combined pharmacotherapy showed higher efficacy including 34 （47 %） vs 17（12 % ）, respectively （P〈0.05 ） ; and combined benzodiazepines were applied to 92 % patients. CONCLUSION： The treatment of eider depression of inpatients with MECT combined with SSRIS are more effective than single drug therapy, and furthermore psychotherapy is still being improved.