牙龈卟啉菌荚膜的热敏感性

Heat sensitivity of capsule from porphromonas gingivalis.

以细胞计数法观察了牙龈卟啉菌荚膜的热敏感性，结果显示：牙龈卟淋菌荚膜在５０℃下，水浴３０ｍｉｎ，活性基本不受影响，６５℃水浴３０ｍｉｎ半量活性成份丧失，８０℃水浴３０ｍｉｎ活性完全丧失，说明牙龈卟啉菌荚膜是─热不稳定性物质。

The experiment showed that the fibroblast-inhibitory activity of capsule form porphromonas gingivalis remained fully inhibitory at temperature of 50℃ or less.When the capsule was pre-incubated for 30min at temperature of 65℃.near 50% of inhibitory activity was lost,whereas fully lost at temperature above 80℃.This finding suggested that capsule from porphromonas gingivalis was a heat-labile material. Due to the heat stability of LPS,the result again indicated that the pathogenic role of capsule had no direct relation with LPS.