DNA随机存储器的设计

Design of DNA random access memory.

近年来,生物大分子在模拟计算领域的研究已经取得了很大的突破,无论是理论模型的研究,还是生化实验的验证,生物分子计算机正蓬勃地展现出它的无可限量的发展前景.DNA随机存储器的研究在整个生物分子计算机研究中是一个重要分支.DNA随机存储器以环状单链DNA分子为存储介质,以4种碱基(腺嘌呤adenine、鸟嘌呤guanine、胞嘧啶cytosine和胸腺嘧啶thymine)对信息进行编码;以DNA分子与各种生化酶(Nicking核酸内切酶、核酸外切酶、聚合酶)间的生化反应来模拟数据的读取和写入.

Recent years, bio-molecules applied in simulating computation has achieved marvelous success, not only in theoretical model study, but also in feasibility validating through biochemical reactions. Bio-molecular computation is blossoming and displaying an unrestricted prospect. DNA random access memory＇s research played an important part in bio-molecular computation＇ research. DNA random access memory takes circular single-stranded DNA as storing matter and uses four nitrogenous bases （Adenine, Guanine, Cytosine and Thymine） to code data. Biochemical reactions between DNA memory and enzymes （Nicking Endonuclease, Exonuclease and Polymerase ） can be defined as reading and writing operations.