摘要
为探讨金石散溶解胆石的药效特点及其作用规律,组织临床协作治疗肝内外胆管结石164例,以B超为主的检查作治疗前后对比。结果表明:164例中痊愈26例(15.85%),有效73例(44.51%),无效65例(39.63%),总有效率60.37%。右肝管结石84例,服药后结石消失10例,变小或减少者44例;左肝管结石34例,结石消失5例,变小或减少者13例;胆总管结石25例,结石消失及变小或减少各10例;多处结石21例.仅1例左、右肝管结石完全消失,除3例无效外,其余均有变小、减少或1处消失的变化。结石长径≤5mm者共10例,有7例完全消失,仅2例无效,疗程以>6个月为佳。胆汁分析显示,金石散具有增进胆汁酸和降低胆红素、粘液及-HCO3-含量的作用。
In order to evaluate the role and mechanism of Jinshisan (JSS) in bile stone dissolution, 164 cases of extra-/intrahepatic biliary stone patients were treated by a collaborated group, the therapeutic effect was observed by B-ultrasonography before and after treatment. Results showed,(1)Among the 164 cases, 26 cases (15. 85%) were cured clinically: 73(44. 51%) were effective and 65 (39.63%) ineffective.(2) After treatment, in 84 patients of right hepatolith, the stone were diappeared in 10 cases, the size or number of stone decreased in 44 casess. In 34 patients with left hepatolith, the figure were 5 and 13 respectively. In 10 cases of choledocholith they were 10 and 10 respectively. While in 21 cases of multiple gallstone, only one case with stones of both sides disappeared, except 3 ineffective cases, others with stone decreased in size or number or disappeared unilaterally. (3) Gallston diappeared in 7 of 10 patients with size of stone ≤ 5 mm, only 2 of them were ineffective.(4) The effect were better in those with treatment course > 6 months. (5) Analyis of bile showed that JSS could increase the amount of bile acid, decrease the bilirubin, mucous and bicarbonate radical in bile.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1996年第1期18-20,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
金石散
肝管结石
溶石
胆汁酸
胆红素
Jinshisan, hepatolith, choledocholith, stone dissolution, bile acid, bilirubin