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榛花对糖尿病小鼠降糖作用及对肝脏和胰岛病理学影响 被引量:7

The Effects of Hazel's Flower for Diabetic Mouse by Alloxan on Decrease Blood Sugar and Pathology in the Liver and Pancreas Islet
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摘要 目的:观察榛花的降血糖作用。方法:采用四氧嘧啶制备实验性糖尿病小鼠模型,以比色分析法测定血糖并通过免疫组织化学和透射电镜观察胰岛B细胞以及通过组织化学观察肝糖原。结果:榛花可降低实验性糖尿病小鼠的血糖水平,未能使胰岛B细胞修复和再生,可提高肝糖原含量。结论:榛花具有降低实验性糖尿病小鼠高血糖的作用,而这种作用可能是通过促进肝组织糖原合成等类胰岛素样作用实现的。 Objective: to observe the effects of hazel's flower on decreasing blood sugar. Methods: by the mouse of experimental diabetes induced by alloxan, by the investigated of colorimetric method,it was measured the blood sugar ,and by the immun -ohistochemistry and transmission electron microscope (TEM),it was observed pancreas islet B cell,and by the histochemistry,it was observed hepatic glycogen. Results: The hazd's flower decreased the lever of the blood sugar and could not make the pancreas islet B cell repaired and regenerated, and increased the contents of hepatic glycogen. Conclusion: The Hazel's flower had the effect of decreasing blood sugar on diabetic mouse induced by alloxan maybe its mechanism of decreasing blood sugar was the insulin kind function of promoting synthesis of hepatic gly-cogen.
出处 《辽宁中医杂志》 CAS 北大核心 2005年第12期1324-1326,共3页 Liaoning Journal of Traditional Chinese Medicine
关键词 榛花 降血糖 胰岛B细胞 肝糖原 hazel's flower decrease blood sugar pancreas islet B cell hepatic glycogen
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