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NON-ISOTHERMAL KINETICS OF THERMAL DECOMPOSITION OF A NOVEL ANTITUMOR AGENT 4-{5-[3,4-DIMETHYL-5-(3,4,5-TRIMETHOXYPHENYL)THIOPHEN-2-YL]-2-METHOXYPHENYL}MORPHOLINE

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摘要 The thermal decomposition of a new antitumor agent,4-{5-[3,4-dimethyl-5-(3,4,5-trimethoxyphenyl)thiophen-2-yl]-2-methoxyphenyl}morpholine was studied by Differential Scanning Calorimetry(DSC)and Thermogravimetry(TG)/Derivative Thermogravimetry(DTG)methods at a flow rate of nitrogen gas of 120 mL/min,The kinetic parameters were obtained from the analysis of the corresponding curves by Kissinger's method,Ozawa's method and the integral method,The results indicate that the apparent activation energy and pre-exponential constants of the decomposition reaction are 106.67 kJ/mol and 10^6.19s^(-1),respectively.
作者 LEI Yingjie SHI Jixian YU Mei 雷英杰;石继仙;俞玫(SCHOOL OF PHARMACEUTICALS AND BIOTECHNOLOGY TIANJIN UNIVERSITY,TIANJIN 300072,CHINA;SCHOOL OF BIOTECHNOLOGY AND CHEMICAL ENGINEERING,TIANJIN UNIVERSITY OF TECHNOLOGY,TIANJIN 300191,CHINA)
出处 《Transactions of Tianjin University》 EI CAS 2006年第1期46-49,共4页 天津大学学报(英文版)
基金 SUPPORTED BY THE NATIONAL YOUNG SCHOLAR AWARD OF NSFC(NO.30125043).
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