转录因子Msx2在犬恒牙牙根发育过程中的表达

Expression of transcription factor Msx2 during permanent tooth root formation of dog

目的观察转录因子Msx2在犬恒牙牙根发育过程中的表达及时空变化,初步探讨其对牙根形态形成的调控作用。方法本研究采用原位杂交技术,对犬恒牙牙根不同发育时期Msx2mRNA的表达进行观察。结果在牙根发育启动期、生长期及成熟期,转录因子Msx2具有不同的时空表达方式。结论Msx2作为牙齿发育过程中重要的转录因子,可能参与牙根形态发育的调控作用。

AIM： To evaluate the regulatory role of transcription factor Msx2 in tooth root patterning by observing the expression of Msx2 during permanent tooth root development of dog. METHODS ： During permanent tooth root formation of dog, Msx2 mRNA was detected by in situ hybridization method. RESULTS ： At stage of tooth root initiation, patterning and maturation, transcription factor Msx2 was detected in a variety of ways of timing and space. CONCLUSION ： Msx2, as a key transcription factors during tooth development, is likely to participate in regulating the formation of tooth roots.