摘要
AIM： To verify the effect of combined interventiona therapy for hepatocellular carcinoma （HCC）. METHODS： The clinical data of 1126 HCC patients who received combined interventional therapy for transcatheter arterial chemoembolization （TACE） before or after hepatectomy, TACE and radio-frequency ablation （RFA）, Chinese medicine treatment and biotherapy after TACE or transcatheter arterial infusion （TAI）, were reviewed according to the results of their liver function, alpha-fetoprotein, image data, color-ultrosonography finding and survival rate. RESULTS： A total of 874 patients were followed up for a period of 2 to 63 mo. The overall 1-, 3- and 5- year survival rates were 67.8%, 28.7% and 18.8% respectively. The 1- 3- and 5- year survival rates of patients who received TACE were 74.7%, 41.4%, 36.9% before hepatectomy and 78.9%, 40.4%, 37.5% after hepatectomy. The effective rate （PR ＋ NC） after TACE and RFA was 93.4%, the 1- and 3- year survival rates were 74.5% and 36.8% after TACE and RFA. The effective rate of PR ＋ NC after TACE was 83.2%. The 1-, 3- and 5- year survival rates were 69.3%, 21.7%, 8.4% after TACE. The effective rate of PR ＋ NC after TAI was 27.5%, the 1- and 2- year survival rates were 11.6% and 0% after TAI. The liver function, color-ultrosonography finding and alpha-fetoprotein after TACE ＋ RFA, TACE and TAI were compared. There was no significant difference in each index between TACE and RFA or TACE as well as in liver function between TACE and RFA or between TACE and TAI. CONCLUSION： The therapeutic effectiveness of TACE before or after hepatectomy is most significant, while the effect of TACE and RFA is better than that of TACE, and the effect of TAI is minimal.
瞄准：为肝细胞癌(HCC ) 验证联合 interventional 治疗的效果。方法：接待了的 1126 个 HCC 病人的临床的数据为 transcatheter 联合了 interventional 治疗动脉的 chemoembolization (不作声)在肝切除术前后，不作声并且无线电频率脱离( RFA )在以后，中国药治疗和简历治疗不作声或 transcatheter 动脉的注入(傣族)，根据他们的肝函数， alpha-fetoprotein ，图象数据， color-ultrasonography 发现和幸存率的结果被考察。结果：874 个病人的一个总数被跟随在上面为 2 ～ 63 瞬间的一个时期。年幸存评估的全面的 1- ， 3- 和 5- 分别地是 67.8% ， 28.7% 和 18.8% 。接待了的病人的幸存率不作声的 1-3- 和 5- 年是 74.7% ， 41.4% ， 36.9% 在肝切除术前并且 78.9% ， 40.4% ， 37.5% 在肝切除术以后。有效的率(PR + NC ) 在以后不作声并且 RFA 是 93.4% ， 1- 和 3- 年幸存率是 74.5% 和 36.8% 在以后不作声并且 RFA。PR + NC 在以后的有效的率不作声是 83.2% 。年幸存评估的 1- ， 3- 和 5- 是 69.3% ， 21.7% ， 8.4% 在以后不作声。PR + NC 的有效的率在傣族是 27.5% 以后， 1- 和 2- 年幸存率在傣族以后是 11.6% 和 0% 。肝功能， color-ultrasonography 发现和 alpha-fetoprotein 在以后不作声 + RFA，不作声，傣族被比较。在每个索引在之间没有有效差量不作声并且 RFA 或象在肝功能在之间一样不作声不作声并且 RFA 或在之间不作声并且傣族。结论：治疗学的有效性在肝切除术前后不作声，是很重要的效果不作声并且 RFA 比的好不作声，并且傣族的效果是最小的。
