摘要
[目的]分析脑灰质异位症伴癫痫的临床特点、脑电图、遗传学机制,提供诊治方案。[方法]回顾性分析2例脑灰质异位症伴癫痫患者的临床、MRI、24h视频脑电图资料,并检索相关文献。[结果]一例患者合并脑裂畸形、透明隔缺如、脑积水、小脑萎缩,十分罕见。2例均采用药物治疗,并跟踪随访,必要时手术治疗。[结论]对于青春型或成人难治性癫痫患者宜早期行MRI检查避免误诊。由于本病目前治疗效果欠佳,有待进一步研究。
[Objective] To analyze the clinical feature, EEG, genetic mechanism of Heterotopic Gray Matter （HGM） with epilepsy and provide diagnostic and therapeutic regimen. [ Methods] The clinical, MRI and 24h-VEEG features of 2 HGM cases were retrospectively inverstigated, and pertinent literature was searched. [ Results] One case of HGM was rare with schizencephaly, septum pellucidum absence, hydrocephaly and cerebellar atrophy. Both the 2 cases accepted drug treatment and follow-up, and surgical operation was conducted when necessary. [Conclusion] We should examine the young or adult intractable epileptic with MRI early to avoid misdiagnosis. We still need further research because of the unsatisfactory therapeutic efficacy.
出处
《现代预防医学》
CAS
北大核心
2007年第5期985-986,共2页
Modern Preventive Medicine
关键词
脑灰质异位症
癫痫
Brain
Heterotopic Gray Matter
epilepsy
