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RNA干扰技术治疗恶性肿瘤的靶点选择和靶向导入 被引量：1

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摘要 一、RNA干扰技术的简介 RNA干扰（siRNA）是指小分子双链RNA抑制同源序列的基因表达的现象，是生物进化过程中保留下来的机制。早期的研究发现RNA干扰参与了植物细胞防御病毒感染和转位子侵袭的免疫反应。2001年Tuchl等发现siRNA能在哺乳动物细胞内高效沉默目标基因的表达，掀起了生命科学领域对siRNA的基础和应用研究的热潮。
作者 宋尔卫
机构地区 中山大学附属第二医院乳腺肿瘤中心
出处 《现代临床医学生物工程学杂志》 2007年第2期126-126,F0003,共2页 Journal of Modern Clinical Medical Bioengineering
关键词 RNA干扰技术 靶向导入 靶点选择 恶性肿瘤 SIRNA 治疗 双链RNA 基因表达
分类号 R730 [医药卫生—肿瘤]
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参考文献10

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同被引文献16

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现代临床医学生物工程学杂志
2007年 第2期

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