Relationship study between platelet count and stage and grade of renal cell carcinoma in indoor patients

Objective:Thrombocytosis has been reported in many types of malignancies and has been studied as a prognostic factor.The aim of this survey is to investigate the relation between platelet count and stage and grade of tumor in indoor patients with renal cell carcinoma(RCC)in order to evaluate the prognostic value of thrombocytosis.Methods:In a descriptive and retrospective survey 82 patients treated by radical nephrectomy for RCC were enrolled.In all cases TNM stage,Fuhrman grade,invasion and platelet count were recorded and entered in SPSS software for analysis.Results:In this study,76 patients(92.7 %)with normal platelet and 6 patients(7.3 %)with thrombocytosis were studied.In this survey there was no significant correlation between the thrombocytosis and pathological stage in all patients,both genders and various age groups.In addition,the correlation between thrombocytosis and nuclear grade was investigated and a significant correlation between them in all patients and both genders was found.Finally,there was no significant correlation between thrombocytosis and nuclear grade at various age groups.Conclusion:Prognostic indicators that can accurately predict survival rates in patients with RCC can be used to select those patients most likely to benefit from adjuvant therapy.In this survey there was a significant correlation between thrombocytosis and nuclear grade,however,further clinical studies are needed.

Objective： Thrombocytosis has been reported in many types of malignancies and has been studied as a prognostic factor. The aim of this survey is to investigate the relation between platelet count and stage and grade of tumor in indoor patients with renal cell carcinoma（RCC） in order to evaluate the prognostic value of thrombocytosis. Methods： In a descriptive and retrospective survey 82 patients treated by radical nephrectomy for RCC were enrolled . In all cases TNM stage, Fuhrman grade, invasion and platelet count were recorded and entered in SPSS software for analysis. Results： In this study,76 patients （ 92.7% ） with normal platelet and 6 patients（7.3% ） with thrombocytosis were studied. In this survey there was no significant correlation between the thrombocytosis and pathological stage in all patients, both genders and various age groups. In addition, the correlation between thrombocytosis and nuclear grade was investigated and a significant correlation between them in all patients and beth genders was found. Finally, there was no significant correlation between thrombocytosis and nuclear grade at various age groups. Conclusion ： Prognostic indicators that can accurately predict survival rates in patients with RCC can be used to select those patients most likely to benefit from adjuvant therapy. In this survey there was a significant correlation between thrombocytosis and nuclear grade , however , further clinical studies are needed.