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广东省2006年乙型病毒性肝炎血清流行病学调查分析 被引量:40

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摘要 目的了解广东省乙型病毒性肝炎(乙肝)流行现状,为制定乙肝防制策略提供科学依据。方法2006年9—10月,采取分层多阶段随机抽样方法,抽取广东省1~59岁居民作为研究样本,开展血清流行病学调查。用酶联免疫吸附试验(ELISA)检测HBsAg、抗-HBs、抗-HBc、HBeAg和抗-HBe。结果共调查3927人,其HBV流行率、HBsAg阳性率、抗-HBs阳性率和抗-HBc阳性率分别为53.65%、11.10%、62.78%和36.76%。1~14岁组HBsAg阳性率和抗-HBc阳性率低于其他年龄组;1~4岁组抗-HBs阳性率高于其他年龄组。在HBsAg阳性者中,1~14岁组HBeAg阳性率高于15~59岁组,而抗-HBe阳性率则低于15~59岁组。结论广东省仍是乙肝高流行区域,今后应进一步加强乙肝防制工作,控制乙肝的流行。
出处 《华南预防医学》 2009年第1期38-40,共3页 South China Journal of Preventive Medicine
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  • 1Weber B.Recent developments in the diagnosis and monitoring of HBV infection and role of the genetic variability of the S gene.Expert Rev Mol Diagn,2005,5:75-91.
  • 2Weber B.Genetic variability of the S gene of hepatitis B virus:clinical and diagnostic impact.J Clin Virol,2005,32:102-112.
  • 3Seddigh-Tonekaboni S,Waters JA,Jeffers S,et al.Effect of variation in the common ‘a' determinant on the antigenicity of hepatitis B surface antigen.J Med Virol,2000,60:113-121.
  • 4Chaudhuri V,Tayal R,Nayak B,et al.Occult hepatitis B virus infection in chronic liver disease:full-length genome and analysis of mutant surface promoter.Gastroenterology,2004,127:1356-1371.
  • 5Allain JP.Occult hepatitis B virus infection:implications in transfusion.Vox Sang,2004,86:83-91.
  • 6Levicnik-Stezinar S.Hepatitis B surface antigen escape mutant in a first time blood donor potentially missed by a routine screening assay.Clin Lab,2004,50:49-51.
  • 7Weber B,Muhlbacher A,Melchior W.Detection of an acute asymptomatic HBsAg negative hepatitis B virus infection in a blood donor by HBV DNA testing.J Clin Virol,2005,32:67-70.
  • 8Allain JP.Occult hepatitis B virus infection.Transfus Clin Biol,2004,11:18-25.
  • 9Yamamoto K,Horikita M,Tsuda F,et al.Naturally occurring escape mutants of hepatitis B with various mutants in the S gene in carriers seropositive for antibody to hepatitis B surface antigen.J Virol,1994,68:2671-2676.
  • 10Shiels MT,Taswell HF,Czaja AJ,et al.Frequency and significance of concurrent hepatitis B surface antigen and antibody in acute and chronic hepatitis B.Gastroenterology,1987,93:675-680.

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