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Cloning of a novel human zinc finger protein(ZNF199)cDNA

Cloning of a novel human zinc finger protein(ZNF199)cDNA
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摘要 ZINC finger proteins play an important role in the regulation of gene expression by binding to DNA/RNA in a sequence-specific manner. Now nearly 200 human zinc finger genes have been cloned. According to the difference of the conservative domain, the zinc finger proteins can be classified into several types.Most of zinc finger proteins belong to the C<sub>2</sub>H<sub>2</sub> type containing the consensus amino acid sequence YECX<sub>2</sub>CX<sub>3</sub>FX<sub>5</sub>LX<sub>2</sub>HX<sub>3</sub>HTGEKP, which is rather conservative especially in the link region between two zinc finger motifs (TGEKP)
机构地区 Fudan Univ
出处 《Chinese Science Bulletin》 SCIE EI CAS 1999年第3期287-290,共4页
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参考文献7

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