3-(2′-苯基-1′,2′,3′-连三唑-4′-基)-6-烷基/芳基-均三唑并[3,4-b]-1,3,4-噻二唑的合成

Synthesis of 3-(2'-Phenyl-1',2',3'-triazole-4'-yl)-6-alkyl/aryl-s-triazolo[3,4-b]-1,3,4-thiadiazoles

研究了3-(2′-苯基-1′,2′,3′-连三唑-4′-基)-4-氨基-5-巯基-1,2,4-三唑(1)与取代苯甲酸和脂肪酸(2a～r)在POCl_3催化下的反应,共合成得到18个新的3-(2′-苯基-1′,2′,3′-连三唑-4′-基)-6-烷基/芳基-均三唑并[3,4-b]-1,3,4-噻二唑(3a～r),经元素分析,IR,~1H NMR和MS进行了结构确证.

Condensation of 3 - (2' - phenyl - 1', 2', 3' - triazole - 4' - yl) - 4 - amino - 5 -mercapto- 1,2,4 - triazole(1) with alkyl or aryl acids (2a^r) in the presence of phosphorus oxychloride gave 18 novel 3 - (2' - phenyl - 1', 2', 3' - triazole - 4' - yl) - 6 - alkyl/aryl - s -triazolo[3,4 - b] - 1,3,4 - thiadiazoles(3a^r). Their structures were confirmed by elemental and spectral analyses.