清气化瘀养阴汤治疗温病气分证的实验研究

Experimental Study on Qingqi Huayu Yangyin Fang for Qi fen Syndrome in seasonal Prevalent Diseases

通过清气汤、清气化瘀汤、清气养阴汤、清气化瘀养阴汤治疗温病气分证动物的实验研究，并与正常组、对照组比较。结果显示：对照组动物脏器组织病理形态学观察见瘀血、出血、微血栓形成及严重炎性改变等指标，证实了温病气分证实验动物已出现ＤＩＣ，属高凝状态。气分阶段不但伤津，且耗血。“耗血”的实质不仅限于血液量的减少，更重要的是表现为血液中血细胞及其它成分的减少，并有功能的严重障碍。各组比较，清气化瘀养阴汤疗效最佳，而单纯用白虎汤效果较差。提示：温病气分阶段存在热炽、血瘀、阴伤的病理变化，治疗必须注重清热、养阴。

The experimental study of Qi fen syndrome in seasonal prevalent diseases(Win Bing) treated with Qingqi Tang, Qingqi Huayu Tang, Qingqi Yangyin Tang and Qingqi Huayu Yangyin Tang was done pespectively, and compared with normal group and control group. The result showed that, in the experimental animals, there were the conditions of DIC and hepercoogulability in Qi fen syndrome, there were not only the impairment of fluids but also the consumption of blood. The charater of blood bonsumption was not only the reduce of blood volume but also mostly the reduce of hemocyte and other blood constituent, accompanied by the serious functional disturbance. In different groups, the effect of Qingqi Huayu Yangyin Tang was the best while that in Baihu Tang (White Tiger Decoction) was worse. It indicates that, the Qi fen syndrome has the pathological changes of intense heat, blood stasis and Yin deficiency. The treatment should be focused on clearing heat, nourishing Yin and activating blood to remove stasis.