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慢性阻塞性肺病患者血沉、红细胞压积、D-二聚体、肺动脉收缩压的相关性 被引量:14

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摘要 目的:探讨慢性阻塞性肺病(COPD)及COPD合并肺动脉高压患者中血沉、红细胞压积、D-二聚体水平的差异及其与肺动脉收缩压的相关性。方法:COPD患者41例,COPD合并肺动高压患者49例,健康者24例,全部检测血沉(ESR)、红细胞压积(HCT)、D-二聚体水平(D-dimer),进行统计分析,以P值<0.05为有统计学意义;COPD合并肺动脉高压组肺动脉收缩压与血沉、红细胞压积、D-二聚体水平相关性以P值<0.10为有统计学意义。结果:(1)COPD患者的ESR较COPD合并肺动脉高压组和健康对照组明显升高,COPD合并肺动脉高压组ESR也较正常对照组明显升高,HCT、D-二聚体在COPD合并肺动脉高压组较COPD组和健康对照组明显升高,COPD组也高于对照组;(2)HCT和D-二聚体与肺动脉收缩压成正相关(r=0.286,P<0.05;r=0.233,P<0.10),ESR和肺动脉收缩压无明显相关(r=-0.195,P>0.10)。结论:在COPD发展至肺心病的过程中,COPD合并肺动脉高压患者HCT相对较高,ESR相对较慢,提示肺心病缺氧时间相对长;HCT和D-二聚体与肺动脉收缩压正相关,提示高凝是导致肺心病的关键因素。
出处 《实用医学杂志》 CAS 北大核心 2009年第19期3238-3239,共2页 The Journal of Practical Medicine
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参考文献8

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