LAK细胞治疗42例中晚期恶性肿瘤的疗效观察

OBSERVATION ON THE TREATMENT OF 42 MIDDLE AND ADVANCED STAGE MALIGNANT CANCER PATIENTS WITH LAK CELLS AND γIL-2

该文报道了来自患者自体或同种异体LAK细胞对 42例中晚期癌症患者的疗效分析 ,其中CR 2例 ,PR 14例 ,MR 12例 ,SD 11例 ,PD 3例。总有效率为 38 10 % ,绝大多数患者都有不同程序的临床症状改善、生活质量提高、生存期延长 ,未观察到严重毒副反应。

This paper reports the results of treating 42 patients with malignant cancer at the middle and advanced stages with γIL-2/LAK cells from the patients peripheral blood and human fetal thymocytes. Two patients experinced complete response (CR), 14 patients experienced partial response (PR), 12 cases minor response (MR), and total curative effects were experienced in 38.10% of the patients. In most of the patients, the clinical symptoms and quality of living improved, and survival time was extended. No severe toxic side effects were observed.