皮肤窦性组织细胞增生症1例

A Case of Cutaneous Sinus Histiocytosis

报告1例皮肤窦性组织细胞增生症(CSH)。患者女,53岁,右侧下颌及左颊部可见浸润性斑块。皮损组织病理示真皮全层组织细胞团块状增生伴淋巴细胞浸润,可见组织细胞吞噬现象。免疫组化染色示:组织细胞S-100蛋白和CD68(+),CD1α标记(-)。现继续治疗中。

To report a 53-year-old female patient suffering from CSH （Cutaneous sinus hietocytosis ）. The purely asymptomatic cutaneous lesions on her submaxilla and cheek were the only clinical manifestation. Histologically, the lesions were marked by characteristic variable numbers of pale-staining histocytes with emperipole- sis overshadowed by extensive lymphoplasmacytic infiltrates in the baekgTound. By immunohistochemmical analysis, the characteristic histoeytes were positive for S-100 protein and CD68, negative for CD1α. treatment with submaxilla seemed ineffective in this case.