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脑脊液寡克隆区带及IgG指数的检测方法临床应用与研究进展 被引量:7

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摘要 早在20世纪40年代初,Kabat发现多发性硬化(MS)患者脑脊液中选择性的γ球蛋白增加,主要是IgG部分增加,而血中无此相应变化,证明了IgG是由中枢神经系统(CNS)内源性局部合成的,由此提出了MS的发病机制与免疫功能异常有关。
出处 《安徽医学》 2010年第12期1534-1537,共4页 Anhui Medical Journal
基金 安徽中医学院临床科学研究基金资助项目(编号:2009LC3-001)
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