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Efficient Syntheses of 2-Substituted Benzimidazoles and Benzoxazoles from β-Keto Esters 被引量:2

Efficient Syntheses of 2-Substituted Benzimidazoles and Benzoxazoles from β-Keto Esters
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摘要 An efficient synthetic method was developed to synthesize 2-substituted benzimidazoles and benzo- xazoles with β-keto esters as starting materials under mild reaction conditions, during which other functional groups are bearable from reactants to products. An efficient synthetic method was developed to synthesize 2-substituted benzimidazoles and benzo- xazoles with β-keto esters as starting materials under mild reaction conditions, during which other functional groups are bearable from reactants to products.
出处 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2011年第2期228-231,共4页 高等学校化学研究(英文版)
基金 Supported by the National Natural Science Foundation of China(No.20874105) the Foundation of Hebei Education Department China(No.2010268)
关键词 BENZIMIDAZOLE BENZOXAZOLE β-Keto ester Benzimidazole Benzoxazole β-Keto ester
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同被引文献22

  • 1CAO Ke,TU YongQiang & ZHANG FuMin P State Key Laboratory of Applied Organic Chemistry and Department of Chemistry,Lanzhou University,Lanzhou 730000,China.Synthesis of substituted benzoxazoles by the iron(Ⅲ)-catalyzed aerobic oxidation process[J].Science China Chemistry,2010,53(1):130-134. 被引量:4
  • 2KAUR A, WAKODE S, PATHAK D E Benzoxazole: The molecule of diverse pharmacological importance[J]. International Journal of Pharmacy and Pharmaceutical Sciences, 2015, 7(1): 16 23.
  • 3SEENAIAH D, REDDY P R, REDDY G M, et al. Synthesis, antimicrobial and cytotoxic activities of pyrimidinyl benzoxazole, benzothiazole and benzimidazole[J]. European Journal of Medicinal Chemistry, 2014, 77: 1-7.
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  • 5WEE D, YOO S, KANG Y H, et al. Poly(imide-benzoxazole) gate insulators with high thermal resistance for solution- processed flexible indium-zinc oxide thin-film transistors[J]. Journal of Materials Chemistry C, 2014, 2: 6395-6401.
  • 6SHARMA H, SINGH N, JANG D O. A ball-milling strategy for the synthesis of benzothiazole, benzimidazole and benzoxazole derivatives under solvent-free conditions[J]. Green Chemistry, 2014, 16(12): 4922-4930.
  • 7BALASWAMY G, SRINIVAS K, PRADEEP P, et al. Synthesis, characterization and antimicrobial activity of novel substituted benzoxazole derivatives[J]. International Journal of Chemical Sciences, 2012, 10(2): 619-626.
  • 8ANAND M, RANJITHA A, HIMAJA M. Silica sulfuric acid catalyzed microwave-assisted synthesis of substituted benzoxazoles and their antimicrobial activity[J]. International Research Journal of Pharmacy, 2011, 2(4): 211-213.
  • 9SOARES A M S, COSTA S P G; GONCALVES M S T. Oxazole light triggered protecting groups: synthesis and photolysis of fused heteroaromatic conjugates[J]. Tetrahedron, 2010, 66(41): 8189- 8195.
  • 10ENDO Y, BACKVALL J E. Biomimetic oxidative coupling of benzylamines and 2-aminophenols: synthesis of benzoxazoles[J]. Chemistry: a European Journal, 2012, 18(43): 13609-13613.

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