摘要
目的探讨糖化血红蛋白测定在糖尿病诊断中的临床意义。方法选择359例糖尿病患者为DM组,正常体检人员92例为对照组,研究两组空腹血糖与糖化血红蛋白的差异,及DM组中空腹血糖与糖化血红蛋白相关性,并以糖化血红蛋白大于8%为试验组,小于8%为对照组,研究两组别并发症及合并症的发生率。结果 DM组与对照组空腹血糖与糖化血红蛋白相比较差异有统计学意义;DM组中空腹血糖与糖化血红蛋白呈正相关,(r=0.634,P<0.01);糖化血红蛋白大于8%的试验组周围神经病变、脂肪肝、高血压、脑血管事件均高于糖化血红蛋白小于8%的组别。结论糖化血红蛋白的测定有助于糖尿病的诊断,对于糖尿病并发症及合并症的监控有重要临床意义。
Objective To investigate the determination of glycated hemoglobin in the diagnosis of diabetes clinical significance. Methods 359 patients with diabetes for the DM group, 92 cases of normal medical personnel for the control group to study the two groups of fasting plasma glucose and glycated hemoglobin differ- ences, and the DM group, fasting plasma glucose and glycosylated hemoglobin in the correlation, and glycated hemoglobin greater than 8% for the test group, less than 8% for the control group, two groups of complications and the incidence of complications. Results DM group and control group results of fasting plasma glucose and glycated hemoglobin compared to a statistically significant difference. DM group, fasting plasma glucose and gly- cared hemoglobin was positively correlated, ( r = 0. 634, P 〈 0.01 ) ; glycated hemoglobin greater than 8% of the test group peripheral neuropathy, fatty liver, hypertension, cerebrovascular events were higher than glycated hemoglobin less than 8% of the group. Conclusion Determination of glycated hemoglobin helps the diagnosis of diabetes, diabetic complications and complications for monitoring have important clinical significance.
出处
《中国实用医药》
2011年第30期28-29,共2页
China Practical Medicine