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用重组纯化M_2抗原检测抗线粒体抗体M_2在原发性胆汁性肝硬化诊断中的意义

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摘要 原发性胆汁性肝硬化（primary biliary cirrhosis,PBC）是一种由免疫介导的慢性进展性疾病,以血清自身抗体和肝内汇管区细胞浸润为特征,主要表现为肝内小胆管进行性破坏与门静脉炎症性改变。高滴度的抗线粒体抗体（anti-mitoc hondrial antibody,AMA）为PBC血清学诊断标志。
作者 刘爱华 张春媚 黄慈波
机构地区 卫生部北京医院风湿免疫科
出处 《中国药物与临床》 CAS 2012年第2期177-179,共3页 Chinese Remedies & Clinics
关键词 原发性胆汁性肝硬化 诊断标志 抗原检测 抗线粒体抗体 炎症性改变 免疫介导 细胞浸润 自身抗体
分类号 R575.2 [医药卫生—消化系统]
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参考文献10

  • 1姜小华,仲人前,孔宪涛.原发性胆汁性肝硬化发病机制研究进展[J].中国免疫学杂志,2002,18(8):586-589. 被引量：19
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二级参考文献18

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中国药物与临床
2012年 第2期

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