碳酸铯存在下铁催化立体选择性合成(Z)-2-亚基-1,4-苯并二噁烷衍生物

Iron-Catalyzed Stereoselective Synthesis of (Z)-2-Ylidene-1,4-benzodioxanes in the Presence of Cs_2CO_3

通过Sonogashira偶联反应合成了邻炔丙基醚苯酚衍生物,在Cs2CO3存在和FeCl3的催化下,进而发生分子内环化反应,立体选择性地合成了一系列(Z)-2-亚基-1,4-苯并二噁烷衍生物.产物的结构通过了1H NMR,13C NMR和HRMS等表征.

A series of monopropargyl catechol derivatives synthesized via the Sonogashira coupling reaction were stereose-lectively converted to（Z）-2-ylidene-1,4-benzodioxanes using FeCl3 as the catalyst,and structurally characterized by 1H NMR,13C NMR and HRMS techniques.