药物中间体p-氨基苯基苄基醚的合成研究

Synthesis of p-aminophenyl benzyl ether as drug intermedium

本论文利用微波技术首次成功地实现了 p -氨基苯基苄基醚化合物的合成 ,对 p -硝基苯基苄基醚的还原也进行了有力的探索 ,并得到满意的结果 .总收率达 84.3% .

p Aminophenyl benzyl ether has been synthesized by reduction of p nitrophenyl benzyl ether. Using microwave radiation technology, p nitrophenyl benzyl ether is synthesized by reaction of p nitrophenol with benzyl chloride. The factors which can affect the reaction have been determined and the yield is 84.3 %.