体外循环心脏术后消化系统并发症的防治进展

Prevention and treatment of gastrointestinal complications following cardiac surgery with cardiopulmonary bypass

体外循环心脏术后消化系统并发症虽然发生率不高,但病死率却极高.体外循环期间多种因素导致消化系统血液供应减少、组织损伤、炎性介质大量释放,从而引起包括胃肠道出血、消化性溃疡、缺血性肠炎、胰腺炎、胆囊炎、肝衰竭等在内的消化系统并发症.严密观察患者临床表现并早期诊断予以干预,对患者的预后有重要帮助.本文就近年来体外循环心脏术后消化系统并发症的机制、危险因素及诊断治疗的进展予以综述.

Acute gastrointestinal complications（GICs） following cardiac surgery with cardiopulmonary bypass（CPB） are rare but carry a high mortality rate.During CPB procedures,many factors cause a reduction of blood supply to the digestive system,tissue injury,and the release of many inflammatory mediators,which can lead to GICs such as gastrointestinal bleeding,peptic ulcers,ischemic enteritis,pancreatitis,cholecystitis,and liver failure.Close observation of clinical manifestations and early diagnosis will help timely manage these complications and improve prognosis.The purpose of this paper is to review the mechanism,risk factors,diagnosis and treatment of GICs after cardiac surgery with cardiopulmonary bypass.