太赫兹科学技术在生物医学中的应用研究

Application of terahertz science and technology in biology and medicine research

介绍了近十年来国内外太赫兹科学技术在生物医学领域的研究与应用进展。重点总结了太赫兹辐射的生物效应、太赫兹光谱技术和太赫兹成像技术,在生物医学领域的研究与应用的3个大类的成果。有关太赫兹辐射的生物效应,分不同频率、不同功率和不同辐射时间下样品的生物学反应来介绍。又根据探测样品属性不同分为生物体、生物组织、生物细胞、生物细胞器和生物大分子等6个层次的内容。充分论证了太赫兹科学技术对生物医学的安全性和适用性。由于太赫兹光谱包含丰富的生物分子及分子间的组成信息和构象信息,在生物医学领域的研究与应用最多。对不同生物大分子的太赫兹特征频谱进行了解读,对太赫兹光谱技术的应用进行了梳理,目的为让更多的人了解太赫兹科学技术的优越性和应用前景。在太赫兹波成像技术方面,总结了其在癌变组织诊断、皮肤烧伤探测等方面的研究应用。为使迷人的太赫兹波科学与技术更好的服务于人类,尝试较为全面地对太赫兹科学技术在生物医学领域取得的研究成果进行归纳与总结,同时也探讨了现阶段在生物医学领域所存在的不足,以及今后努力的方向。

The overview of research and applications about terahertz science and technology in the biomedical field over the last decade home and abroad is introduced. The results of three major categories of research and application in- cluding biological effects of terahertz radiation, terahertz spectroscopy and terahertz imaging technology are summarized. According to the properties of test sample, 6 contents about organism, tissue, biological cells, biological organelles and biological macromolecules etc. are respectively introduced. The safety and applicability in biology and medicine of tera- hertz science and technology are fully demonstrated. Terahertz spectra contains a wealth of biological molecules, molecu- lar composition and conformational information used for research and applications in the biomedical field. This paper de- scribes the characteristics of terahertz spectrum of different biological macromolecules different interpretations, and the application of terahertz spectroscopy, in order to let more people understand the advantages and application prospects of terahertz science and technology. Also the paper summarizes the research application of terahertz imaging technology in cancerous tissue diagnosis, skin burns detection etc. We try a more comprehensive induction and conclusion of terahertz science and technology in the field of biomedical research achievements, but also discuss the shortcomings, as well as the direction of future efforts, so as to the terahertz science and technology serves to humanity better.