摘要
目的:研究夜磨牙(sleep bruxism,SB)患者睡眠期咀嚼肌节律性运动(RMMA)发生的微觉醒机制。方法 :对30名夜磨牙患者、30名正常人进行连续2夜的多导睡眠监测,研究RMMA事件与微觉醒(MA)的时间相关性;比较2组间RMMA指数及MA指数的差异;RMMA事件发生前60 s、前40 s、前20 s、前5 s,共5个时间点的各连续10个心动周期的平均心率,以及RMMA事件发生前后各5个心动周期的心率变化。结果:夜磨牙症患者微觉醒指数(7.72±1.21)与正常对照相似(7.53±1.33,P=0.5641);但咀嚼肌节律性运动频率,即磨牙指数[(6.10±1.05)次/h]约3倍于正常对照组[(1.81±0.39)次/h,P<0.0001)]。RMMA事件与MA存在高度时间相关性。夜磨牙患者RMMA事件发生前1个心动周期开始心率明显加快。结论:夜磨牙患者较正常人群有较高的RMMA频率,RMMA与睡眠微觉醒相关,磨牙事件发生时伴随明显的心脏交感神经活动增加。
Objective: To investigate whether rhythmic mastieatory muscle activity (RMMA) is associated with sleep micro- arousals (MA), and analyze the association between RMMA of sleep bruxism patients (RMMA/SB) and autonomic cardiac activity. Methods: Thirty SB subjects and thirty control subjects for two consecutive nights were performed by polygraphic recordings. MA index and RMMA index were scored. The mean heart rate from a series of 10 cardiac cycles was calculated at 60, 40, 20 and 5 sec before RMMA onset respectively. To assess a transient beat-to-beat heart rate change in relation to the RMMA onset, heart rate from 5 cardiac cycles before and 5 cycles after the onset were also calculated. Results: Sleep bruxism (SB) subjects showed a higher incidence of rhythmic masticatory muscle activity (RMMA) than control subjects (6.10±1.05 vs. 1.81±0.39, P〈0.0001). However, no difference was found in according to their micro-arousal index(7.72±l.21 vs.7.53±1.33, P=0.5641). RMMA/SB was associated with sleep micro-arousals. In both groups, transient heart rate acceleration was observed in relation to the onset of RMMA episodes. Conclusion: RMMA is associated with sleep micro-arousals. In SB subjects, a clear increase in sympathetic activity precedes SB onset.
出处
《口腔颌面外科杂志》
CAS
2012年第6期401-404,共4页
Journal of Oral and Maxillofacial Surgery
基金
国家自然科学基金(30700960)
上海市青年科技启明星(10QA1407400)
关键词
夜磨牙
心率变化
微觉醒
睡眠周期
sleep bruxism
heart rate variability
micro-arousals
sleep cycles