脉搏轮廓心输出量监测联合连续血液净化治疗在急性呼吸窘迫综合征中的临床体会

Clinical experience of PiCCO plus associated with CEBP in treating ARDS

目的探讨PiCCO(脉搏轮廓心输出量监测)联合连续血液净化(CEBP)在治疗急性呼吸窘迫综合征(ARDS)的临床疗效。方法 2008年5月～2011年6月间收治的42例ARDS患者在常规治疗的基础上采用PiCCO指导下CEBP治疗,观察患者治疗前后的生命体征、血气分析指标、生化指标、炎症因子、病死率。结果治疗后患者的氧合,呼吸,心率,炎症因子、PiCCO指标血管外肺水(EVLWI)等较治疗前有显著好转,病死率低,对循环影响小。结论 PiCCO联合CEBP治疗能降低ARDS患者的血管外肺水,清除炎症介质,改善氧合,维护内环境,显著降低病死率,改善了ARDS的预后,是治疗ARDS的有效方式。

Objective To explore the clinical effect of PiCCO plus associated with CEBP when treating ARDS. Methods We used PiCCO plus associated with CEBP on 42 ARDS patient from May 2007 to June 2011 besides conventional therapy . And we observe the patients＇ vital signs, blood gas analysis, biochemistry index, inflammatory factor, mortality. Results After trea- ting, the patients＇ oxygenation, respiration ,heart rate, inflammatory factors, E VLWI turn for the better obviously. The death rate is on the decline and the effect of circulation is small. Conclusion PiCCO plus associated with CEBP can reduce the EVLW of ARDS patients, clear inflammatory factor , improve oxygenation , maintain internal environment, reduce the death rate , improve ARDS patients＇ prognosis.