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EGFR-TKI有效肺癌经“药物间歇”后再获TKI敏感 被引量:2

Regain of TKI Sensitivity Following A Drug Holiday for Patients with NSCLC Who Initially Responded to EGFRTKI Treatment
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摘要 1文献来源 Becker A, Crombag L, Heideman DA, et al. Retreatment with Erlotinib: Regain of TKI sensitivity following a drug holiday for patients with NSCLC who initially responded to EGFR-TKI treatment [J]. Eur J Cancer, 2011,47(17) :2603-2606.2
出处 《循证医学》 CSCD 2013年第1期50-53,共4页 The Journal of Evidence-Based Medicine
关键词 非小细胞肺癌 耐药 表皮生长因子受体 氨酸激酶抑制剂 厄洛替尼 non-small cell lung cancer resistance epidermalgrowth factor receptor (EGFR) tyrosine kinase inhibitors(TKI) Erlotinib
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  • 1WANG Meng-zhao LI Long-yun WANG Shu-lan ZHANG Xiao-tong ZHONG Wei ZHANG Li.EFFICACY AND SAFETY OF GEFITINIB AS MONOTHERAPY FOR CHINESE PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER[J].Chinese Medical Journal,2006(1):63-68. 被引量:12
  • 2Chaft JE,Oxnard GR,Sima CS. Disease flare after tyrosine kinase inhibitor discontinuation in patients with EGFR-mutant lung cancer and acquired resistance to Erlotinib or Gefitinib:Implications for clinical trial design[J].Clinical Cancer Research,2011,(19):6298-6303.
  • 3Nishie K,Kawaguchi T,Tamiya A. Epidermal growth factor receptor tyrosine kinase inhibitors beyond progressive disease:A retrospective analysis for Japanese patients with activating EGFR mutations[J].JOURNAL OF THORACIC ONCOLOGY,2012,(11):1722-1727.
  • 4Oxnard GR,Lo P,Jackman DM. Delay of chemotherapy through use of post-progression Erlotinib in patients with EGFR-mutant lung cancer[J].Journal of Clinical Oncology,2012,(15suppl):abstr7547.
  • 5Sarah BG,Geoffrey RO,Subba D. Chemotherapy with Erlotinib or chemotherapy alone in advanced NSCLC with acquired resistance to EGFR tyrosine kinase inhibitors (TKI)[J].Journal of Clinical Oncology,2012,(15suppl):abstr7524.
  • 6ZHU Yu-jia,XIA Ying,REN Guan-jun,WANG Meng-zhao,ZENG Xuan,ZHANG Li.Efficacy and clinical/molecular predictors of erlotinib monotherapy for Chinese advanced non-small cell lung cancer[J].Chinese Medical Journal,2010(22):3200-3205. 被引量:3

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