自制颈椎翼型钛网的生物力学评价

Biomechanical Evaluation for a Pterygo-Shape Titanium Mesh Cage

目的对自行研制的中下颈椎前路内固定装置——新型翼型钛网进行生物力学测试,评价其生物力学稳定性,为产品初步临床应用提供理论依据。方法取25具新鲜青年男性尸体颈椎标本,制成5种状态脊柱功能单位(FSU)的试验模型:正常颈椎组、失稳颈椎模型组、髂骨植骨组、钢板+髂骨植骨组和新型翼形钛网组,每组5具标本。利用脊柱三维运动分析系统依次测定各组在不同运动状态下颈椎节段(C4-6)运动范围(ROM)变化,进行统计分析,比较新型翼形钛网组与单纯髂骨组、钢板+髂骨组对失稳颈椎的稳定作用。结果生物力学测试表明,新型翼形钛网内固定系统可以对失稳颈椎提供有效的稳定作用,与失稳颈椎节段的运动范围比较差异有显著性(P<0.01),其抗前屈和抗后伸功能超过正常颈椎(P<0.05),而其抗旋转抗扭曲功能与钢板系统存在一定差距(P<0.05)。结论新型翼形钛网内固定系统具有较好的生物力学稳定性,可以对中下颈椎前路减压融合提供有效的稳定作用。

Objective To study one kind of internal fixation ——new pterygo-shape titanium mesh cage in anterior cervical,evaluate the biomechanical stability,and povide the theory basis for the product further improvement design and the preliminary clinical application.Methods Twelve fresh cervical spine specimens（C1-7） from young male cadavers were used to establish normal contrast,destabilizing cervical vertebrae,ilial crest strut graft,the eurous plate internal fixation,the new pterygo-shape titanium mesh cage internal fixation.Biomechanical stability analysis were performed by testing cervical vertebrae（C4-6） range of motion（ROM） in sequence.The stabilization of the New Pterygo-ShapeTitanium Mesh Cage internal fixation and the euros plate internal fixation was compared for destabilizing cervical vertebrae.Result The biological mechanics test indicated,new pterygo-shape titanium mesh cage may provide the effective stabilization to the destabilizing cervical vertebrae,which had the remarkable difference compared with the destabilizing cervical vertebrae stage movement scope（P0.01）.Its anti-antefexion and anti-postextend function exceeded norma cervical vertebrae（P0.05）.Its anti-revolution and anti-curvature were inferior to the plate（P0.05）.Conclusion New pterygo-shape titanium mesh cage has the good biological mechanics stability,wihich can provide the effective stabilization to the under cervical vertebra anterior decompression fusion.This system operation is simple,and has broad clinical application prospect.