产γ-PGA批式发酵动力学模型的建立被引量：6

Establishment of a kinetic model for γ-polyglutamic acid with batch fermentation

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摘要以一株γ-PGA(γ-聚谷氨酸)高产菌枯草芽孢杆菌HCUL-B115为实验菌株,在5L发酵罐中进行分批发酵,并测定发酵过程中的生物量、残糖量、前体物残量和γ-聚谷氨酸产量。应用MATLAB软件进行最优参数估计和非线性拟合,得到了菌体生长、产物生成和底物消耗的动力学模型和模型参数。结果表明,所建立的批式发酵动力学模型能较好地反映γ-PGA批式发酵规律。 With high yield γ-PGA strain Bacillus subtilis HCUL-B115 as experimental strain,batch fermentation in 5L fermenter.The concentration of cell,residual glutamic acid and sugar content,γ-poly glutamic acid were determined in the process of fermentation.The kinetic models for cell growth,poly γ-glutamic acid production and substrate consumption were proposed with MATLAB software.The results showed that the models could provide a reasonable description for the batch fermentation of poly γ-glutamic acid.

作者梁金钟王风青张露露

机构地区哈尔滨商业大学食品工程学院黑龙江省高等学校食品科学与工程重点实验室

出处《食品工业科技》 CAS CSCD 北大核心 2013年第16期174-177,共4页 Science and Technology of Food Industry

基金国家支撑项目(2012BAD32B08)

关键词 Γ-聚谷氨酸动力学模型枯草芽孢杆菌 poly-γ-glutamic acid fermentation kinetic model Bacillus subtilis

分类号 TS202.3 [轻工技术与工程—食品科学]

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