胎膜早破与孕妇生殖道UU和CT感染的关系

Relationship between premature rupture of membranes and urogenital ureaplasma urealyticum and chlamydia trachomatis infection

目的探讨胎膜早破与孕妇生殖道解脲支原体(UU)、沙眼衣原体(CT)感染关系及其对妊娠结局的影响。方法选取201 1年2月至2012年2月在南通市妇幼保健院分娩的胎膜早破孕妇150例作为观察组,同期正常分娩无胎膜早破孕妇150例作为对照组,取宫颈分泌物进行解脲支原体和沙眼衣原体检测,同时比较两组妊娠结局。结果两组UU检出率比较差异无统计学意义(x^2=3.396,P>0.05);CT检出率,观察组孕妇明显高于对照组,差异有统计学意义(x^2=15.860,P<0.01)。观察组孕妇的早产、剖宫产、低出生体重儿、胎盘绒毛膜羊膜炎的发生率明显高于对照组,两组比较差异均有统计学意义(x^2值分别为38.048、22.371、15.381、12.459,均P<0.05)。结论胎膜早破与孕妇生殖道解脲支原体和沙眼衣原体感染密切相关,胎膜早破可致不良妊娠结局发生几率增加。

Objective To investigate the relationship between premature rupture of membranes and urogenital ureaplasma urealyticum （UU） and chlamydia trachomatis （CT） infection, and to explore the effect of premature rupture of membranes on pregnant outcomes. Methods From February 2011 to February 2012 150 cases of premature rupture of membranes delivering in Nantong Maternity and Child Health Care Hospital were selected as observation group, and control group included 150 cases of normal pregnant women without premature rupture of membranes giving birth in the same period. Cervical secretions of them were taken to perform UU and CT testing. Meanwhile, pregnant outcomes of two groups were compared. Results Comparing two groups, the difference in UU prevalence was not statistically significant （χ2 = 3. 396, P 〉 0.05 ）. The prevalence of CT of the observation group was obviously higher than that of the control group, and the difference was significant （χ2 = 15. 860, P 〈 0.01 ）. The incidence of premature labor, cesarean section, low-birth-weight infant and placental chorioamnionitis in the observation group was obviously higher than that of the control group, and the differences were statistically significant （χ2 value was 38. 048, 22. 371, 15. 381 and 12. 459, respectively, all P 〈 0.05 ）. Conclusion Premature rupture of membranes is closely related with UU and CT infection, and it may cause the increase of incidence of adverse pregnancy outcomes.