分离红细胞回输自体血浆治疗老年肺心病高粘血症的临床应用

Clinical application of separating RBC and autoplasmotherapy in treating senile cor pulmonale with hyperviscosity syndrome

目的 分离出多余的红细胞 ,降低老年肺心病高粘血症的血液粘度 ,以改善心肺功能。方法 每例病人每天采血 2 0 0ml,共采 3次 ,血液进行离心、热合、分浆 ,分离出的红细胞废弃 ,血浆立即通过保留的静脉通道 ,全部回输给病人。结果 细胞压积下降 1 71% ,全血粘度低切变平均下降 0 72 ,血浆比粘度平均下降 0 0 5 ,血红蛋白平均下降 1.2 8g L ,经统计学处理均有显著性差异 (P <0 .0 1)。结论 该疗法降低了高粘血症的血液粘度 ,改善了心肺功能。

Objective Separating supernumerary RBC to cure hyperviscosity syndrome and to improve cardio pulmonary function in senile patients with cor pulmonale.Methods 200ml blood was pumped from each senile cor pulmonale patient with hyperviscosity syndrome,qd for three days and the blood was centrifuged,heated.The RBC separated was abandoned.Then the plasma was sent back to the patient through the reserved vein immediately.Results Packed cell volume descended for 1.71%,whole blood specific viscodity descended for 0.72 ,plasma specific viscosity descended for 0.05,hemoglobin descended for 1.28g/L averagely.All the numerical value above had remarkable differences in statistics( P <0.01).Conclusion The blood viscosity can be descended and cardio pulmonary function can be improved by the method.