妊高征患者红细胞免疫粘附调节因子活性的测定

The activity of regulatory factors of red cell immune adheresion in pregnancy induced hypertention

目的 :通过测定妊高征 (PIH)患者红细胞免疫粘附 (RCIA)调节因子活性 ,探讨PIH患者红细胞免疫功能改变的原因。方法 :测定 40例PIH患者和 30例正常孕妇的RCIA促进因子活性和抑制因子活性及红细胞补体受体花环率(RBCC3bRR% )、红细胞免疫复合物花环率 (RBCICR % )。结果 :与正常孕妇相比 ,PIH患者RCIA抑制因子活性明显升高 ,RBCC3bRR%及RBCICR %明显降低 (P <0 .0 1) ,RCIA促进因子活性无明显变化 (P >0 .0 5 )。结论 :PIH患者红细胞免疫功能原发低下 。

TheTo investigate the relationshop between pregnancy-induced hypertention (PIH) and regulatory factors of red cell immune adheresion (RCIA). Methods:The rosette experiments on the activity of regulatory factors of RCIA (promotive and inhibitory factors) and the red cell receptor (RBCC 3b RR%) and immune compelex (BRCICR%) were determinated in 40 cases of PIH and 30 normal pregnant women. Results:Compared with normal pregnant women, the activity of RCIA inhibitory factor of cases in PIH was increased significantly (P<0.01), RBCC 3b RR% and RBCICR% were decressed significantly (P<0.01), the activity of RCIA promotive factor was changed significantly (P>0.05). Conclusions:The red cell immune function of the patients with PIH are originally low, which might be relative to the activity of RCIA inhibitory factor.