含黄芪血清对淋巴细胞增殖及IL-2产生的影响

Effect of the Serum with Radix Astragali on Lymphocyte Proliferation and Production of the Interleukin 2

黄芪煎剂浓缩液和含黄芪小鼠血清均对小鼠脾淋巴细胞增殖、混合淋巴细胞培养反应及ＩＬ２的产生有促进作用，且表现出剂量依赖性。表明黄芪煎剂在体内外均具有促进淋巴细胞增殖、混合淋巴细胞培养反应及ＩＬ２产生的作用。

? Objective:To further evaluate the immunopharmacological effects of Radix Astragali.Methods:Two in vitro experiments were performed for comparative study to evaluate the immunopharmacological effects of Radix Astragali by serologic pharmacological test.The first experiment approach adopted the addition of the mice's serum pretreated with Radix Astragali to the culture medium while in the second experiment the Radix Astragali was added to the medium directly.Results:Both the serum with Radix Astragali and the Radix Astragali itself could promote the lymphocyte proliferation,mixed lymphocyte response and the production of the interleukin 2 significantly and dosedependently.Conclusions:It suggested that Radix Astragali could promote the lymphocyte proliferation,mixed lymphocyte response and the production of the interleukin 2 both in vivo and in vitro.Radix Astragali contain the effective elements of promoting the lymphocyte proliferation,mixed lymphocyte response and the production of the interleukin 2 and it is orally effective.