中药荆芥的单萜类化合物

Monoterpenoids from Schizonepeta tenuifolia

目的 对传统中药荆芥 Schizonepeta tenuifolia(Benth.) Briq.中的单萜类化学成分进行研究。方法 溶剂提取、柱层析分离纯化、光谱测定化学结构。结果 从中药荆芥的全草中分离得到 2个新的和 3个已知的单萜类化合物。结论 根据理化性质和光谱数据 ,新化合物的结构鉴定为 3-羟基 - 4(8) -烯 -对 -薄荷烷 - 3(9) -内酯 ;1,2 -二羟基 - 8(9) -烯 -对 -薄荷烷。

Object To study the chemical constituents of Schizonepeta tenuifolia (Benth.) Briq.. Methods The monoterpenoid constituents of S. tenuifolia were separated on silica gel column and their structures were elucidated by spectral. Results Two new compounds and three known compounds were obtained. Conclusion The new compounds were identified as 3-hydroxy-4(8)-ene-p-menthane-3(9)-lactone and 1, 2-dihydroxy-8(9)-ene-p-menthane.