肝硬化左心功能彩色多普勒超声显像观察

Left Ventricular Function of Liver Cirrhosis Observed by Color Doppler Echocardiac lmage

目的 探讨肝硬化高动力循环对心功能的影响。方法 应用彩色多普勒超声检查 2 8例肝硬化患者和 2 0例正常人左室收缩末内径 ,舒张末内径 ,二尖瓣口E峰、A峰峰值流速、VE/VA比值、E峰减速时间 (DT)和左室等容舒张松弛时间 (IVRT) ,评价左室收缩、泵血功能和左室舒张功能。结果 肝硬化患者左心收缩、泵血功能与正常人无显著差异 (P >0 .0 5 ) ,但左心舒张功能减低 (P <0 .0 5 ) ,肝硬化失代偿合并腹水的患者舒张功能受累尤为严重 (P <0 .0 5 )。结论 在肝硬化高动力循环状态下 ,心室舒张功能减低 ,收缩。

Objective To study cardiac function in hyperdynamic circulation of liver cirrhosis.Methods A total of 28 cirrhotic patients and 20 healthy controls were studied by color Doppler echocardiography.Left ventricular systolic function and ejection function were evaluated by left ventricular end systolic volume and left ventricular end diastolic volume.Left ventricular diastolic function was evaluated by the peak filling velocity of E wave (VE) and A wave (VA),E/A ratio, the deceleration time of E wave (DT),the left ventricular isovolumic relaxation time (IVRT).Results Between cirrhotic patients and healthy controls,there was not significant difference in systolic function and ejection function( P >0.05).But cirrhotic patients experienced a decrease in diastolic function, and cirrhotic patients with ascites showed more serious ( P <0.05) than cirrhotic patients without ascites.Conclusion In patients with liver cirrhosis,ventricular diastolic function decreased,ventricular systolic function and ejection function had not change under the hyperdynamic circulation.