循经感传现象产生机理的探讨

Study on Mechanisms of the Propagated Sensation Along Meridians

目的:探讨外周感觉神经末梢间是否存在跨节段的远距离信息传递以及此信息传递的特点。方法:分离神经细束,观察逆行电刺激大鼠脊神经背侧皮支后,相距较远的神经细束上机械感受单位的电活动变化。结果:记录的单位主要是Aσ和C类单位,其感受野多位于距背中线0.5～2.0cm的范围内。机械感受单位一般在跨节段电刺激后的91～120s传入放电增加;刺激T9在T12记录的单位和刺激T12在T9记录的单位,二者放电增加反应相似;另外,T10、T11脊神经与中枢断开和不断开两种情况下所记录的单位放电也未见明显不同。结论:外周末梢间的信息传递具有传导速度较慢,传递线路相对稳定,且具有不受中枢调控和双向性的特点,可能是形成循经感传的生理学基础。

Purpose To approach to long distance information transmission between peripheral sensory nerve endings and properties of this information transmission. Methods The effects of antidromic electrical stimulation of the spinal nerves on the discharges of the remote mechanoreceptive units in rats were observed by isolating filaments of the dorsal cu-tanous branches. Results The recorded units were mainly Aσ- and C-neurons units. The receptive field of the units mainly located within the scope of 0.5-2.0 cm around the middle line of the back. The discharge frequency of mechanoreceptive units increased significantly during 91-120 seconds after the stimulation. Similar increasing responses of the discharge were observed when T9 was stimulated to record T12 units, and when T^ was stimulated to record T9 and vice versa. In addition, in the cases of the dissection and the non-dissection of T10 and T11 from the spinal cord, no significant differences were found between the two groups in terms of the property or the discharge increase. Conclusion There exists the long distance information transmission between peripheral nerve endings, characterized by a slow conductive velocity, relatively stable transmission routes, and bi-directional transmission independent of central modulation. The long distance transmission forms possibly the physiological basis of the propagated sensation along meridians.