烟雾病患者脑缺血面积影像学分析及其与空腹血糖的相关性研究

Correlation of ischemic area and fasting plasma glucose in patients with cerebral smoke

目的探讨烟雾病患者脑缺血面积与空腹血糖的关系。方法选取经颅脑CT平扫及头颈部CT血管造影(CTA)扫描确诊,并经数字减影血管造影(DSA)证实的烟雾病的患者40例,同时测量其空腹血糖,回顾性分析烟雾病患者脑缺血面积与空腹血糖的相关关系。结果烟雾病患者40例根据空腹血糖水平分组:正常空腹血糖(FPG)组18例;空腹血糖受损(IFG)组6例,糖尿病组16例;其中FPG正常组存在脑梗死患者15例,占83%(15/18);IFG组存在脑梗死患者5例,占83%(5/6);糖尿病组存在脑梗死患者15例,占94%(15/16);本组烟雾病脑梗死面积大小与空腹血糖值的高低具有统计学意义(χ2=53.8,P<0.01)。即烟雾病患者脑梗死的发病程度与血糖增高的程度呈正相关关系(rs=0.649,P<0.01)。结论烟雾病患者脑缺血面积与血糖高低具有相关关系,烟雾病并发血糖值越高患者脑缺血发病程度越严重。

Objective To investigate the relationship between cerebral ischemia in patients smoke area and fasting blood sugar. Methods By brain CT scan and diagnosed with head and neck CTA scans, and by patients with moyamoya disease DSA confirmed 40 cases, simultaneous measurement of fasting glucose, retrospective analysis of patients with cerebral ischemic area of the smoke and the correlation between fasting glucose. Results Forty patients with moyamoya disease based on fasting glucose levels were diveded into 3 groups： normal fasting glucose （fasting plasma glucose, FPG）of 18 cases; impaired fasting glucose （impaired fasting glucose, IFG） group of 6 cases , 16 cases of diabetes. Normal fasting glucose group existed 15 cases with cerebral infarction ,accounting for 83%（15/18）; existed 5 cases of cerebral infarction in IFG group, accounting for 83%（5/6）;presence of 15 cases of cerebral infarction in diabetic group, accounting 94%（15/16）. The level of the group the size of moyamoya disease and cerebral infarction fasting glucose values were statistically significant （χ2=53.8, P〈0.01）. That was the extent of the disease severity and hyper-glycemia in patients with cerebral infarction smoke positively correlated （rs=0.649, P〈0.01）. Conclusion Smoke area with cerebral ischemia in patients with blood glucose level correlation between higher blood glucose moyamoya disease com-plicated by cerebral ischemia in patients with more severe disease severity.