969名1～14岁藏族儿童乙型肝炎病毒感染的影响因素研究

Factors influencing Hepatitis B Virus Infection among 969 Tibetan Children Aged 1 to 14 Years

目的探讨1-14岁藏族儿童乙型肝炎（乙肝）病毒（Hepatitis B Virus,HBV）感染的主要影响因素。方法对2006年全国乙肝血清流行病学调查中,969名1-14岁藏族儿童采用单因素和二元逻辑斯蒂（Logistic）回归分析HBV感染者。结果有乙肝疫苗（Hepatitis B Vaccine,HepB）免疫史是儿童免受HBV感染的保护因素,居住城市、无HepB免疫史、有口腔诊疗史和创伤性美容史是儿童感染HBV的危险因素。结论继续推广目前实施的HepB免疫策略,加强对新生儿的首剂及时、全程、合格的HepB接种,控制医源性感染,开发有当地文化特色阻断HBV传播的健康教育策略。

Objective Explore factors that influence hepatitis B virus（ HBV） infection among Tibetan children aged 1 to 14 years.Methods Based on the national hepatitis B serum epidemiological survey in 2006,univariate analysis and binary logistic regression were used to determine the influential factors of HBV infection among 969 Tibetan children from 1 to 14 years old.Results History of hepatitis B vaccination was a protective factor to avoid HBV infection.Living in urban areas,not having hepatitis B vaccination history,dental treatment history,and traumatic ear piercing history were risk factors for HBV infection of children.Conclusions The current hepatitis B immunization strategy should be enhanced,especially the immunization strategy of the timely birth dose for newborns,and completing 3 timely doses of HBV vaccine.Hospital-acquired infections should be strictly controlled.Specific health strategies should be developed based on local culture.