自制接骨膏外敷联合祛风止痛胶囊治疗膝骨关节炎临床疗效观察

Efficacy of the self-made external bone-knitting ointment combined with the dispelling wind to relieve pain capsule on the treatment of knee osteoarthritis

目的研究祛风止痛胶囊口服联合自制接骨膏外敷治疗双膝骨关节炎临床运用疗效。方法将我院2010年6月-2013年6月期间我科门诊或住院病人中80例膝骨性关节炎患者采用随机数字表法分为治疗组与对照组,每组40例。治疗组应用祛风止痛胶囊口服联合自制接骨膏外敷治疗;对照组采用硫酸氨基葡萄糖胶囊及双氯芬酸钠肠溶片口服治疗,12w为一疗程,疗程结束后比较随访疗效。结果治疗组总有效率达87.5%,优于对照组(χ2=10.6,P<0.05)。治疗组与对照组治疗后症状及体征比较有统计学意义(t=3.35,P<0.05),治疗组与对照组治疗后Womac关节炎指数评分及KOA严重程度治疗指数比较有差异性(t=4.14,P<0.05)。结论运用自制接骨膏外敷联合祛风止痛胶囊口服治疗双膝骨关节炎能显著改善患者膝关节骨关节炎的临床症状和关节功能。

Objective To study the efficacy of the self-made external bone-knitting ointment combined with the dispelling wind to relieve pain capsule on the treatment of knee osteoarthritis in the clinic.Methods Eighty out-and in-hospital patients with knee osteoarthritis during June 2010 to June 2013 were randomly divided into treatment group and control group,with 40 cases in each group.Patients in the treatment group received the self-made external bone-knitting ointment combined with the dispelling wind to relieve pain capsule.Patients in the control group received glucosamine sulfate capsules and enteric-coated diclofenac sodium tablets orally.One course of treatment lasted for 12 weeks.The efficacy was followed up and compared between the groups after the treatment.Results The efficacy in the treatment group was 87.5%,which was better than that in the control group（χ2= 10.6,P 0.05）.The symptoms and signs between the treatment group and the control group were statistically significant（t = 3.35,P 0.05）.After the treatment,the Womac arthritis index score and the severity of KOA treatment index between the treatment group and the control group were statistically significant（t = 4.14 P 0.05）.Conclusion The use of the self-made external boneknitting ointment combined with the dispelling wind to relieve pain capsule significantly relieves the clinical symptoms and improves the function of the knee joint in patients with osteoarthritis.