制药废水中磷霉素和α-苯乙胺的生物降解及相互作用

Biodegradation and interactions of fosfomycin and α-phenylethylamine in pharmaceutical wastewater

以比耗氧速率SOUR、呼吸抑制率和发光细菌光损失为衡量指标,研究了在磷霉素、α-苯乙胺及其混合物作用下,活性污泥和发光细菌的可生化性和急性毒性的变化.结果表明,α-苯乙胺的急性毒性和对活性污泥的呼吸抑制率均大于磷霉素.α-苯乙胺与磷霉素混合液的可生化性和急性毒性两者在混合物中的比例有关,当α-苯乙胺所占比例低于25%时,混合液的可生化性基本不受两者比例的影响;但当α-苯乙胺所占比例高于25%时,混合液的可生化性随着α-苯乙胺所占比例的增加而降低.当混合液中α-苯乙胺所占比例为25%时,其急性毒性最低.

Specific oxygen uptake rate（SOUR）, respiratory inhibitory rate of activated sludge and light loss from luminous bacteria were used as indicators, biodegradability and acute toxicity of fosfomycin, α-phenylethylamine as well as their mixtures were investigated. The results showed that the acute toxicity and respiratory inhibitory rate of α-phenylethylamine were higher than those of fosfomycin. The biodegradability and acute toxicity of their mixtures highly depended on the ratios of α-phenylethylamine. For instance, biodegradability of the mixtures didn＇t change when the ratio of α-phenylethylamine was lower than 25%. However, biodegradability of the mixtures decreased while the ratio of α-phenylethylamine exceeded 25%. The acute toxicity of the mixture was the lowest when the ratio of α-phenylethylamine was 25%.