摘要
目的探讨核素89SrCl2对骨转移瘤患者的治疗效果。方法 75例肿瘤患者经全身骨扫描显像证实存在多发性骨转移瘤,使用核素89SrCl2治疗后,通过统计分析比较治疗前后骨痛的缓解程度、外周血象的改变及骨转移灶变化情况。结果核素89SrCl2治疗骨转移瘤疗效明确,75例患者中60例疼痛出现不同程度的缓解,缓解率达80%(P<0.01),其中19例患者疼痛完全消失;而治疗前后外周血象无明显改变;患者骨转移灶缓解率达89%(P<0.01)。结论核素89SrCl2对骨转移瘤患者的止痛效果好,毒副反应小,且骨转移灶缓解率高,是一种有效的治疗手段。
Objective To investigate the therapeutic effects of strontium-89 therapy in patients with bone metastases. Methods Seventy-five cancer patients with multiple bone metastases confirmed with whole body bone scan imaging were treated with strontium-89. The catabolic effects of bone pain, the changes of peripheral hemogram and bone metastases lesions were analyzed before and after strontium-89 therapy. Results Among seventy-five cases of patients, sixty cases appeared different degree of pain relief, and the remission rate was 80% (P 〈 0. 01 ); Nineteen patients pain disappeared completely. There was no significant change for peripheral hemogram during treatment period and the bone metastases remission rate in all cancer patients was 89% (P 〈0.01 ). Conclusion Strontium-89 therapy is an effective therapeutic method for patients with bone metastases with favorable effects on relieving pain, low reaction of toxicity and high remission rate.
出处
《标记免疫分析与临床》
CAS
2014年第5期540-542,共3页
Labeled Immunoassays and Clinical Medicine
关键词
89SrCl2
骨转移瘤
肿瘤
核素治疗
Nuclide strontium-89
Bone metastasis
Cancer
Radionuclide therapy