肺炎支原体感染与儿童哮喘的相关性（英文）

Association of Mycoplasma pneumoniae infection and childhood asthma

Mycoplasma pneumoniae is a frequent cause of acute respiratory infections in both children and adults.It can cause pharyngitis,otitis,tracheobronchitis,or community-acquired pneumonia,but may also remain totally asymptomatic.Mycoplasma pneumoniae is an organism that reportedly has a strong relationship to asthma.The role of atypical bacterial infection in the pathogenesis of asthma is a subject of continuing debate.There is an increasing body of literature concerning the association between Mycoplasma pneumoniae(M.pneumoniae)and asthma pathogenesis.Moreover,many studies investigating such a link have been uncontrolled and have provided conflicting evidence,in part due to the difficulty in accurately diagnosing infection with these atypical pathogens.Large,general population-based prospective studies are necessary to investigate the development of asthma induced by M.pneumoniae infection in humans.This manuscript will review the relationship between M.pneumoniae infection and childhood asthma.