10年前简易智能状态检查量表项目分与痴呆发病关系的多因素分析

A multi-factor analysis of the relationship between changes of item scores of MMSE and the incidence of dementia in community elderly

目的 探索社区老年人群认知功能的动态变化规律以及简易智能状态检查量表(MMSE)项目分对痴呆的预测价值。 方法 对上海市静安区非痴呆老年人群进行中文版MMSE调查 ,并于 10年后随访。按是否发展为痴呆 ,分为非痴呆组和痴呆组。 结果 (1)两次查访资料完整者 1192例 ,10年后随访发现 12 4例痴呆患者 (10 4 % ) ;(2 )痴呆组多数基线项目分显著性高于非痴呆组 ;(3)对痴呆的预测中 ,时间定向、连续减 7计算、阅读理解项目具有显著性意义。 结论 量表的项目分析是MMSE的重要信息之一。

Objective To study the rule of dynamic change of cognitive function in community elderly and predicting for dementia through using items of MMSE. Methods A 10 year follow up of cognitive function survey was carried out in the non dementia old people using Chinese version Mini Mental State Examination(MMSE). The elder people were divided into two groups (dementia group and non dementia group) according to the DSM Ⅲ R diagnostic criteria 10 years later. Results (1) A total of 1 192 subjects completed all data sheets by two surveys and 124 cases(10 4%)were identified in the second survey 10 years later. (2)Almost all the baseline item scores and its change of MMSE of the dementia group were higher than that of the non dementia group. (3)Orientation of time, serial subtration by seven, reading items of MMSE were effective predictors for the dementia, resding and orientation of time were significant predictors for Alzheimer's disease through logistic regression model. Conclusions The item analysis of MMSE is important information for the epidemiological research.