摘要
艾滋病合并肺部感染的研究多以临床观察为主,且缺少中成药的应用研究,有必要在临床研究设计方面遵循多中心、随机、多盲的原则,选好中医药的临床治疗切入点,凸显中医药防治艾滋病合并肺部感染的优势。同时观察患者用药前后症状、体征、安全性指标、临床免疫及炎症指标的主化,探讨中药在患者体内的抗炎作用机制和对免疫功能的影响,为药物作用机制的研究和临床疗效评价提供参考,为艾滋病合并肺部感染临床路径的实现提供支撑。
At present, the study on AIDS with the infection of pulmonary infection is mainly based on clinical observation, and lack of traditional Chinese medicine research. Therefore, it is necessary to follow the principle of multi center, randomized, muhicenter clinical study design, selecting good Chinese medicine clinical treatment starting point, highlighting the advantages of Chinese medicine in the prevention and treatment of AIDS complicated with pulmonary infection. Before and after treatment in patients with symptoms, signs, safety index, clinical immunology and inflammation markers were observed at the same time, defining the traditional Chinese medicine patient anti-inflammatory effect and the influence on immune function, which can provide a reference for research on the mechanism of drug action and evaluation the clinical efficacy, and provide support for clinical pathway implementation to AIDS patients with pulmona- ry infection.
出处
《中医学报》
CAS
2015年第8期1079-1081,共3页
Acta Chinese Medicine
基金
国家十二五科技重大专项(2013ZX10005001001)
国家中医临床研究基地业务建设科研专项(JDZX2012020)
郑州市科技局科技领军人物专项(13IPLJRC671)
河南省中医管理局科学研究专项(2013ZY01001)
关键词
艾滋病
肺部感染
风邪袭肺证
风寒袭肺证
痰热壅肺证
痰湿阻肺证
肺肾两亏证
肺脾气虚证
肺阴不足证
痰瘀阻肺证
AIDS
pulmonary infection
pathogenic wind attacking the lung syndrome
syndrome of wind cold attacking the lung
phlegmheat obstructing the lung syndrome
phlegm-damp obstructing the lung syndrome
lung and kidney deficiency syndrome
lung and spleendeficiency syndrome
lung Yin deficiency syndrome
phlegm and blood stasis obstructing the lung syndrome
