纯中药内服外敷治疗痤疮后色素沉着临床观察

Clinical observation of the curative effects of acne pigmentation with pure traditional Chinese medicine

目的:观察自拟方纯中药内服外敷治疗痤疮后色素沉着的疗效,寻找一种有效、副作用小的中医治疗方法。方法:采用随机、对照、单盲的研究方案,将符合纳入标准的76例患者随机分为两组,治疗组:38例,自拟方中药内服及外敷中药微粉面膜治疗;对照组:外用千白氢醌乳膏(2%氢醌乳膏又名氢醌霜)治疗。观察两组治疗前、治疗30d、60d后色素程度、色素沉着面积的变化。结果:两组患者治疗30d、60d后各项积分变化在色素程度、色素沉着面积及总积分方面比较(P<0.05),有显著性差异;两组疗效比较(P<0.05),有显著性差异,治疗组疗效明显优于对照组。结论:自拟方纯中药内服外敷综合疗法具有显著的促进面部色素沉着消退的作用。

Objective Observation of the curative effects of decoction of pure external medicine in acne pigmentation,to find an effective treatment method by traditional Chinese medicine. Methods A randomized,controlled,single blind study,will meet the inclusion criteria of 76 patients were randomly divided into two groups.Treatment group：In 38 cases,The effect of traditional Chinese medicine and traditional Chinese medicine micro noodle die treatment （treatment group）;Control group：For Qianbai Hydroquinone Cream（2% Hydroquinone Cream aka Qing Kunshuang）treatment （referred to as the control group）.Observe the two groups before treatment,30 days,60 days after the degree of pigmentation,pigmentation area changes. Results Two groups of patients treated for 30 days,60 days after the changes in the score of the degree of pigmentation,pigmentation area and the total score,P〈0.05.The two groups showed significant difference in treatment group：Efficacy evaluation：Cured 6 cases,markedly effective in 18 cases, effective in 14 cases,invalid in 0 cases,the total effective rate was 100%：Control group：Cured 0 cases, markedly effective in 7 cases,effective in 23 cases,invalid in 8 cases,the total effective rate was 78.9% .Comparison of efficacy of the two groups P〈0.05,There were significant differences between the two groups,the curative effect of the treatment group was significantly better than that of the control group.Conclusion The effect of pure traditional Chinese medicine comprehensive therapy has a significant role in promoting the facial pigmentation faded.