舒心通络丸质量标准研究

Study on Quality Standard of Shu Xin Tong Luo Pill

目的建立舒心通络丸的质量标准。方法采用TLC法鉴别方中黄芪、丹参、川芎、红花和远志;采用HPLC法测定陈皮中橙皮苷的含量。结果黄芪、丹参、川芎、红花和远志TLC色谱斑点清晰,专属性好;橙皮苷在0.3255μg^2.1700μg范围内线性关系良好(r=0.9999),平均加样回收率为98.86,RSD=1.37%。结论该薄层色谱鉴别方法斑点清晰、专属性强、重现性好,含量测定方法分离度好、结果准确,可有效控制舒心通络丸的质量。

Objective： to establish the quality standard of Shu Xin Tong Luo Pill. Methods： the TLC method was used to identify Radix Astragali,radix salviae miltiorrhizae,Rhizoma Chuanxiong,safflower and Radix Polygalae. The content of dried tangerine peel hesperidin was determined by HPLC. Results： Radix Astragali,radix salviae miltiorrhizae,Rhizoma Chuanxiong,safflower and Radix Polygalae TLC spots were clear,reproducible; hesperidin in 0. 3255 muon G - 2. 1700 muon g linear relations of good（ r = 0. 9999）,the average recovery was 98. 86,RSD = 1. 37 %. Conclusion： the TLC identification method has clear spots,strong specificity,good reproducibility,good separation degree and accurate results,which can effectively control the quality of Shu Xin Tong Luo Pill.